BDBM50118812 (2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide::(2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide::(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrofuran-2-carboxamide::(3R,4S,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide::(3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide::(N-6-(3-iodobenzyl)adenosine-5'-N-methyluronamide::3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide::CHEMBL119709::IB-MECA::N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12
InChI Key InChIKey=HUJXGQILHAUCCV-MOROJQBDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 50118812
Affinity DataKi: 3.70nMAssay Description:Binding affinity for human adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.98nMAssay Description:Displacement of [125I]ABA from human adenosine A1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Mus musculus)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptors of bovine cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of radioligand from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of [3H]-R-PIA binding to human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]CCPA from human A1 receptor expressed in CHO cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Binding affinity to adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]R-PIA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Binding affinity towards recombinant human Adenosine A1 receptor was determined using [3H]R-PIA (2.0 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity for A1-adenosine receptor by the displacement of specific [3H]-PIA binding in rat brain was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity against adenosine A1 receptor in rat brain membranes using [3H]R-PIA.More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Tested for the binding affinity of A1 receptor by displacing the [3H]-PIA in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CHA from Adenosine A1 receptor in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity for adenosine A1 receptor as displacement of [3H]R-PIA from rat brain membranes at 10e-4 MMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Ability to displace radioligand [3H]- DPCPX from adenosine A1 receptor on rat cortical membrane in the absence of GTPMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CHA binding to Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CCPA from recombinant human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]CCPA from rat adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of radioligand from rat adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Displacement of [3H]N6-phenylisopropyladenosine from recombinant human A1AR expressed in CHO cell membranes after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Displacement of [3H]R-PLA from human adenosine A1 receptor expressed in CHO cells after 60 mins by liquid scintillation analyzerMore data for this Ligand-Target Pair